The latest research has found that a
chemical compound commonly found in coffee may help prevent some of the
damaging effects of obesity and weight gain. Researchers at the University of
Georgia report in Pharmaceutical Research that chlorogenic acid, or CGA,
significantly reduced insulin resistance and accumulation of fat in the livers
of mice who were fed a high-fat diet.
Aside from weight gain, two common
side effects of obesity are increased insulin resistance and the accumulation
of fat in the liver. Left untreated, these disorders can lead to diabetes and
poor liver function.
“Previous studies have shown that
coffee consumption may lower the risk for chronic diseases like Type 2 diabetes
and cardiovascular disease,” said Yongjie Ma, a postdoctoral research associate
in UGA's College of Pharmacy and lead author of the paper.
“Our study expands on this research
by looking at the benefits associated with this specific compound, which is
found in great abundance in coffee, but also in other fruits and vegetables
like apples, pears, tomatoes and blueberries.”
“We're not suggesting that people
start drinking a lot of coffee to protect themselves from an unhealthy
lifestyle,” said Ma, who is also a member of UGA's Obesity Initiative. “But we
do think we might be able to create a useful therapy with CGA that will help
those at risk for obesity-related disease as they make positive lifestyle
changes.”
For more about the study, visit http://news.uga.edu/releases/article/chemical-in-coffee-may-help-prevent-obesity-related-disease/.
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